The Holy Grail of Chronic Kidney Disease (CKD) is not dialysis or even a transplant, but a viable artificial kidney. There has been ongoing research, but there also seems to be little progress. I have posted about The Kidney Project (TK) a few times as they seem to be the only significant artificial kidney project.
UCSF released some news a few days ago that seems to point to some significant progress. TKP said they have successfully tested a prototype bioartificial kidney. There is a YouTube video that explains further:
Basically, TKP was able to produce a hemofilter that filters out toxins from the bloodstream using membranes made from silicon semiconductor wafers. They also made a bioreactor with “renal tubule cells” that will maintain fluid balance and other metabolic functions. Combined, the hemofilter and bioreactor is implanted like a transplanted kidney, and powered via the patient’s blood pressure. It sounds awesome if it actually works. There are currently ~93,000 people waiting for a kidney transplant due to a shortage of donated organs. A viable artificial kidney will improve quality of life for a lot of people.
My biggest fear after the kidney transplant is EOL organ rejection. If the transplanted kidney fails before I die, then I will need to go back on dialysis. Likely I will be ~70 years old by then so the chances for another kidney transplant will be very low. If an artificial kidney is readily available, that could be another option.