When I was on hemodialysis the first time, I would get a lot of cramps in both my upper and lower legs. This was usually due to removing too much fluid during the dialysis session. Things would be better during the six months of peritoneal dialysis as leg cramping became rare. Likewise, when I was back on hemodialysis the second time, there were occasional cramps, but nothing like the frequency or intensity before.
For about a year after transplant, I would still get occasional cramps, but more often in my ankles rather than legs. This subsided about six months ago, so I was quite surprised to have both calf muscles cramp hard early yesterday morning. My right leg cramped so hard that my calf muscle was sore for the entire day. Thankfully, the cramps did not return this morning and things are fine again.
My lab results were mostly normal, so it is not due to low sodium, potassium, or phosphorus. I have been peeing a lot recently, so I am not dehydrated either. Strange.